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Targeted Therapy in Translational Cancer Research by Apostolia-Maria Tsimberidou

Targeted Therapy in Translational Cancer Research Apostolia-Maria Tsimberidou ebook
ISBN: 9781118468579
Format: pdf
Page: 400
Publisher: Wiley

Biomarkers and clinical trials. Targeting prostatic tumor micro-environment to address therapy resistance. The local control on therapy enables higher tumor treatment efficacy, while simultaneously reducing off-target effects. Reports from the 2010 Clinical and Translational Cancer Research Think Tank meeting: design strategies for personalized therapy trials. A same trend was also observed in the TIVO-1 trial, in which tivozanib and sorafenib were compared as initial targeted therapy for metastatic RCC (7). Recently, targeted therapy, and especially drugs that target EGFR, has been shown to be a promising therapeutic method against lung cancer. The goal of our research group is to understand the biological mechanisms used for future development of targeted therapies, including cell and gene therapy. Five breakout groups discussed the following areas: Cancer biology and drug development. In cancer cells many signaling pathways operate in parallel, hence the idea of multi-targeted therapy is prevailing. The Society of Translational Cancer Research held its biennial on a variety of topics related to multi-targeted therapeutic approaches. Models, and the design of clinical trials for targeted therapies. Prestigious editorial board members of Translational Cancer Research Advances in Radiotherapy and Targeted Therapies for Lung cancer. However, with the advent of targeted therapeutic strategies in non-small cell is renewed optimism in lung cancer research for this subgroup of patients. 2008 Oct Statistical issues in translational cancer research. An Update on Immunohistochemistry in Translational Cancer Research diagnosis, prediction of outcome or response to molecular-targeted therapies. The BU Cancer Center research activities are organized into three Programs: two (T1 Translational Cancer Research Program and the Hormone-Responsive Cancers Cancer Genetics and Progression; Targeted Therapeutic Approaches. Breast Cancer Research Foundation-AACR Grants for Translational Breast Project: PKC-delta as a therapeutic target in colon cancer. Table 2 Unpublished or still recruiting clinical trials with novel anti-HER2 therapies or targeted agents to reverse or prevent Trastuzumab resistance.